Demecolcine (Colcemid)

In vitro / Animal

Mechanism of Action

Analogous antimitotic activity to colchicine; arrests cells at metaphase through tubulin binding

Research Notes

Used in cytogenetics laboratories to arrest cells at metaphase for karyotyping. Explored as a less toxic antineoplastic congener. Moderate evidence from in vitro and laboratory applications.

Found In 1 Herb

Autumn Crocus

Western

3D Molecular Structure

Alkaloid

Drag to rotate · Click atoms to explore

Demecolcine (Colcemid)

AlkaloidNitrogen-containing compounds with potent pharmacological effects

Representative pattern: C₉H₇N₂O

Atoms

Nitrogen

Carbon

Hydrogen

Oxygen

Related Compounds (Alkaloid)

3-Demethylcolchicine(1)Brahmine(1)Christembine(1)Colchicine(1)Fragarine(1)Host-derived alkaloids (variable)(1)Muscarine(1)Punarnavine(1)Pyrrolizidine alkaloids (trace)(1)Sambucine(1)Speciogynine(1)Taspine(1)

Live Research

Open on PubMed

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare practitioner before using any herbal product.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This content is for educational purposes only and is not a substitute for professional medical advice.