Christembine

In vitro

Mechanism of Action

Modulates cholinergic neurotransmission in helminths by acting as an acetylcholine receptor agonist at neuromuscular junctions of parasites, causing spastic paralysis. Also demonstrates mild analgesic activity through peripheral pain pathway modulation.

Research Notes

VidangaAyurvedic

Isolated from Embelia ribes root bark and demonstrated anthelmintic activity in in vitro assays against Ascaris suum and Haemonchus contortus. Limited pharmacokinetic data available. Activity appears complementary to the benzoquinone compounds (embelin, vilangin).

Found In 1 Herb

Vidanga

Ayurvedic

3D Molecular Structure

Alkaloid

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Christembine

AlkaloidNitrogen-containing compounds with potent pharmacological effects

Representative pattern: C₉H₇N₂O

Atoms

Nitrogen

Carbon

Hydrogen

Oxygen

Related Compounds (Alkaloid)

3-Demethylcolchicine(1)Brahmine(1)Colchicine(1)Demecolcine (Colcemid)(1)Fragarine(1)Host-derived alkaloids (variable)(1)Muscarine(1)Punarnavine(1)Pyrrolizidine alkaloids (trace)(1)Sambucine(1)Speciogynine(1)Taspine(1)

Live Research

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