Wogonin

In vitro / Animal

Mechanism of Action

CDK9/cyclin T1 inhibition, pro-apoptotic, anti-inflammatory via COX-2 inhibition, GABA-A receptor positive allosteric modulator

Binds benzodiazepine site of GABA-A receptor; anti-inflammatory; antioxidant

Research Notes

Scutellaria (Huang Qin)TCM

Anxiolytic effects via GABA-A receptor modulation in animal models. Anti-cancer activity in multiple cell lines via CDK9 inhibition and apoptosis induction. Anti-inflammatory comparable to indomethacin.

SkullcapWestern

Selective anxiolytic without significant sedation in animal models; neuroprotective in vitro

Found In 2 Herbs

Scutellaria (Huang Qin)

TCM

Skullcap

Western

3D Molecular Structure

Flavone

Drag to rotate · Click atoms to explore

Wogonin

FlavoneBioactive phytochemical with therapeutic properties

Representative pattern: C₁₅H₁₀O₃

Atoms

Carbon

Oxygen

Related Compounds (Flavone)

Chrysin(1)Flavonoids (luteolin, apigenin)(1)Hispidulin(2)Jaceosidin(1)Luteolin(14)Tricin(3)

Live Research

Open on PubMed

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