Morindone

Antimicrobial studies demonstrate moderate activity against Staphylococcus aureus and Pseudomonas aeruginosa, though minimum inhibitory concentrations are generally higher than conventional antibiotics. MAO-B inhibition data derive primarily from in vitro enzyme assays; clinical relevance and in vivo activity require further investigation. The contribution of morindone to noni's traditional analgesic reputation has not been directly substantiated in clinical research.