Geniposide

In vitro / Animal

Mechanism of Action

Metabolised to genipin by gut bacteria; anti-inflammatory, choleretic, neuroprotective via GLP-1R activation; hepatotoxic at high doses

Research Notes

Gardenia (Zhi Zi)TCM

Neuroprotective in Alzheimer's models via GLP-1 receptor agonism. Choleretic effect supports traditional use for jaundice. Hepatotoxicity documented at high doses — genipin causes hepatocyte apoptosis via mitochondrial pathway.

Found In 1 Herb

Gardenia (Zhi Zi)

TCM

3D Molecular Structure

Iridoid glycoside

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Geniposide

Iridoid glycosideSugar-bound molecules that control drug release in the body

Representative pattern: C₁₁H₁₄O₆

Atoms

Carbon

Oxygen

Related Compounds (Iridoid glycoside)

Acteoside(1)Agnuside(2)Antirrhinoside(1)Aucubin(8)Catalpin (iridoid glycoside)(1)Catalpol(6)Catalpol (iridoid glycoside)(1)Echinacoside(1)Lamalbide(1)Ligustroside(1)Monotropein(1)Morroniside(1)

Live Research

Open on PubMed

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