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Aucubin

Clinical trial

Mechanism of Action

Primary anti-inflammatory and hepatoprotective iridoid; also demonstrates mild diuretic, antiviral, and antioxidant activity; well-characterised in the Plantaginaceae family
Anti-hypertensive via endothelial NO production; hepatoprotective; anti-inflammatory; collagen synthesis promotion
Major iridoid glycoside; exhibits anti-inflammatory activity and protects mucosal integrity in ophthalmic and respiratory tissues
Anti-inflammatory and hepatoprotective activity documented in other plant contexts; contributes to overall iridoid glycoside load
Anti-inflammatory through NF-kB inhibition; hepatoprotective; antimicrobial against gram-positive bacteria
Anti-inflammatory; hepatoprotective; antimicrobial
Anti-inflammatory via NF-kB inhibition; hepatoprotective; antimicrobial
Hepatoprotective; anti-inflammatory; promotes wound healing; antimicrobial

Research Notes

BrooklimeWestern

Aucubin is extensively studied in Plantago and related genera. Anti-inflammatory, hepatoprotective, and antimicrobial activity documented in multiple preclinical models. Specific studies on Veronica beccabunga aucubin are limited but class pharmacology is well established.

Aucubin is the primary iridoid in Eucommia bark. Clinical trials demonstrate blood pressure reduction and improvements in lower back pain.

EyebrightWestern

Aucubin is a well-characterised iridoid with demonstrated anti-inflammatory effects in multiple tissue models. Protects mucosal integrity and has shown hepatoprotective properties in related studies.

Well-studied iridoid with anti-inflammatory, hepatoprotective, and antimicrobial activity in preclinical models.

MulleinWestern

Aucubin demonstrates broad anti-inflammatory activity. In vitro studies confirm activity against Staphylococcus aureus and Streptococcus species relevant to ear and respiratory infections.

Anti-inflammatory via NF-kB inhibition in animal models; hepatoprotective; found in multiple plant genera (Plantago, Verbascum, Pedicularis)

PlantainWestern

Aucubin from plantain demonstrates significant anti-inflammatory and antimicrobial activity, supporting traditional use as a wound herb and respiratory demulcent.

Aucubin provides hepatoprotective and anti-inflammatory effects. Raw form retains higher iridoid content supporting heat-clearing and blood-cooling applications.

Found In 8 Herbs

3D Molecular Structure

Iridoid Glycoside
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Aucubin

Iridoid GlycosideSugar-bound molecules that control drug release in the body

Representative pattern: C₁₁H₁₄O₆

Atoms
Carbon
Oxygen

Related Compounds (Iridoid Glycoside)

Live Research

Open on PubMed

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This content is for educational purposes only and is not a substitute for professional medical advice.