Beta-glucans

Moderate

Mechanism of Action

Branched fungal cell-wall polysaccharides recognized as pathogen-associated molecular patterns (PAMPs) by the innate immune system. Bind to Dectin-1 receptor on macrophages and dendritic cells, activating downstream signaling through Syk kinase and NF-kB pathways. Enhance phagocytosis, reactive oxygen species production, and pro-inflammatory cytokine secretion. Support antioxidant defense by enhancing superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) enzyme activity.

Research Notes

Tiger Milk MushroomMushroom

Preclinical studies on L. rhinocerus beta-glucan fractions demonstrated significant enhancement of macrophage phagocytic activity, NK cell cytotoxicity, and T-cell proliferation. Antioxidant studies confirmed scavenging of reactive oxygen species and enhanced endogenous antioxidant enzyme activity. Clinical evidence from human supplementation trials supports improved respiratory function and immune parameters over 4–12 week supplementation periods.

Found In 1 Herb

Tiger Milk Mushroom

Mushroom

3D Molecular Structure

Polysaccharide (beta-1,3/1,6-glucan)

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Beta-glucans

Polysaccharide (beta-1,3/1,6-glucan)Complex carbohydrate polymers that modulate immune response

Representative pattern: (C₆H₁₀O₅)ₙ

Atoms

Carbon

Oxygen

Related Compounds (Polysaccharide (beta-1,3/1,6-glucan))

Beta-glucan polysaccharides(1)Pleuran(1)

Live Research

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This content is for educational purposes only and is not a substitute for professional medical advice.