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Beta-glucan polysaccharides
PreliminaryMechanism of Action
Activate innate immune cells by binding to Dectin-1, complement receptor 3 (CR3), and toll-like receptors on macrophages and dendritic cells. Trigger phagocytic and cytotoxic activities, stimulate production of reactive oxygen and nitrogen intermediates, and enhance natural killer cell function through cytokine-mediated signaling.
Research Notes
Tinder PolyporeMushroom
Immunomodulatory effects of F. fomentarius polysaccharides were demonstrated in experimental mice, with direct activation of leukocytes and enhanced phagocytic and cytotoxic activity. Extracellular polysaccharides showed anti-proliferative effects on gastric carcinoma cells and promoted secretion of anti-tumor cytokines in HepA mouse tumor models. All evidence remains at the preclinical level.
Found In 1 Herb
3D Molecular Structure
Polysaccharide (beta-1,3/1,6-glucan)
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Beta-glucan polysaccharides
Polysaccharide (beta-1,3/1,6-glucan)Complex carbohydrate polymers that modulate immune response
Representative pattern: (C₆H₁₀O₅)ₙ
Atoms
Carbon
Oxygen
Related Compounds (Polysaccharide (beta-1,3/1,6-glucan))
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