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Beta-glucan polysaccharides

Preliminary

Mechanism of Action

Activate innate immune cells by binding to Dectin-1, complement receptor 3 (CR3), and toll-like receptors on macrophages and dendritic cells. Trigger phagocytic and cytotoxic activities, stimulate production of reactive oxygen and nitrogen intermediates, and enhance natural killer cell function through cytokine-mediated signaling.

Research Notes

Immunomodulatory effects of F. fomentarius polysaccharides were demonstrated in experimental mice, with direct activation of leukocytes and enhanced phagocytic and cytotoxic activity. Extracellular polysaccharides showed anti-proliferative effects on gastric carcinoma cells and promoted secretion of anti-tumor cytokines in HepA mouse tumor models. All evidence remains at the preclinical level.

Found In 1 Herb

3D Molecular Structure

Polysaccharide (beta-1,3/1,6-glucan)
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Beta-glucan polysaccharides

Polysaccharide (beta-1,3/1,6-glucan)Complex carbohydrate polymers that modulate immune response

Representative pattern: (C₆H₁₀O₅)ₙ

Atoms
Carbon
Oxygen

Related Compounds (Polysaccharide (beta-1,3/1,6-glucan))

Live Research

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