Xysmalobin

Preliminary

Mechanism of Action

Synergistic intestinal smooth muscle relaxant acting alongside uzarin via partial Na⁺/K⁺-ATPase inhibition in the gut wall; also reported to inhibit prostaglandin-mediated secretory diarrhoea through suppression of intestinal adenylate cyclase activity.

Synergistic intestinal smooth muscle relaxant acting alongside uzarin; contributes to antispasmodic effect via partial Na⁺/K⁺-ATPase inhibition in gut wall; also reported to inhibit prostaglandin-mediated secretory diarrhoea.

Research Notes

UzaraAfrican

Less studied independently than uzarin; in vitro studies confirm antispasmodic activity on isolated intestinal preparations. The combined pharmacological profile of uzarin and xysmalobin underlies the standardised extract's efficacy as documented in registration studies for the European market.

UzaraAfrican

Less studied independently than uzarin; in vitro studies confirm antispasmodic activity on isolated intestinal preparations. Combined pharmacological activity of uzarin and xysmalobin underlies the standardised extract's efficacy profile.

Found In 2 Herbs

Uzara

African

Uzara

African

3D Molecular Structure

Cardenolide cardiac glycoside

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Xysmalobin

Cardenolide cardiac glycosideSugar-bound molecules that control drug release in the body

Representative pattern: C₁₁H₁₄O₆

Atoms

Carbon

Oxygen

Related Compounds (Cardenolide cardiac glycoside)

Uzarin(2)

Live Research

Open on PubMed

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