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Xanthotoxin (8-methoxypsoralen / ammoidin)
Clinical trialMechanism of Action
Intercalates with DNA under UVA irradiation forming monoadducts and crosslinks; inhibits keratinocyte proliferation in psoriasis and stimulates melanogenesis in vitiligo; used as pharmaceutical methoxsalen
Research Notes
Bishop's Weed (Ammi)Western
Pharmaceutical methoxsalen (derived from this compound) is the basis of PUVA phototherapy — one of the most significant translations of traditional herbal medicine into modern dermatological practice. Extensive clinical trial evidence supports efficacy in vitiligo and psoriasis.
Found In 1 Herb
3D Molecular Structure
Linear Furocoumarin
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Xanthotoxin (8-methoxypsoralen / ammoidin)
Linear FurocoumarinBioactive phytochemical with therapeutic properties
Representative pattern: C₇H₆O₃
Atoms
Carbon
Oxygen
Hydrogen
Related Compounds (Linear Furocoumarin)
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