Bergapten (5-methoxypsoralen)

Clinical trial

Mechanism of Action

Co-occurring photosensitising furocoumarin contributing to melanogenesis stimulation under UV; synergistic with xanthotoxin in phototherapy

Photosensitising compound that intercalates DNA upon UV activation; therapeutically used in PUVA therapy for psoriasis and vitiligo

Research Notes

Bishop's Weed (Ammi)Western

Photosensitising activity documented. Also present in bergamot oil and many Apiaceae species. Contributes to the overall PUVA activity of Ammi majus preparations.

Wild ParsnipWestern

Well-established photosensitiser used clinically in PUVA therapy. Documented phototoxicity risk requires sun protection during use.

Found In 2 Herbs

Bishop's Weed (Ammi)

Western

Wild Parsnip

Western

3D Molecular Structure

Linear Furocoumarin

Drag to rotate · Click atoms to explore

Bergapten (5-methoxypsoralen)

Linear FurocoumarinBioactive phytochemical with therapeutic properties

Representative pattern: C₇H₆O₃

Atoms

Carbon

Oxygen

Hydrogen

Related Compounds (Linear Furocoumarin)

Xanthotoxin (8-methoxypsoralen / ammoidin)(1)

Live Research

Open on PubMed

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