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Saikosaponin D
In vitro / AnimalMechanism of Action
Anti-inflammatory, anti-fibrotic, anti-cancer (autophagy induction), hepatotoxic at high doses via mitochondrial apoptosis
Research Notes
Anti-cancer effects via autophagy induction in multiple cancer cell lines. Anti-fibrotic in hepatic stellate cell models. Hepatotoxic at high doses — causes hepatocyte apoptosis via mitochondrial pathway — basis for Bupleurum hepatotoxicity reports.
Found In 1 Herb
3D Molecular Structure
Oleanane-type triterpene saponin
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Saikosaponin D
Oleanane-type triterpene saponinAromatic plant metabolites with anti-inflammatory properties
Representative pattern: C₁₁H₁₄O₆
Atoms
Carbon
Oxygen
Related Compounds (Oleanane-type triterpene saponin)
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