Isoalchorneine

In vitro / Animal

Mechanism of Action

Contributes to anti-inflammatory activity through inhibition of 5-lipoxygenase (5-LOX) pathway, reducing leukotriene synthesis. May also modulate TNF-alpha and IL-1beta expression in activated macrophages.

Research Notes

IporuruSouth American

In vitro studies on lipopolysaccharide-stimulated macrophages showed dose-dependent suppression of pro-inflammatory cytokines by A. castaneifolia bark extract, with isoalchorneine identified as a contributing active compound. Animal models of carrageenan-induced paw edema demonstrated significant anti-inflammatory effects.

Found In 1 Herb

Iporuru

South American

3D Molecular Structure

Guanidine alkaloid

Drag to rotate · Click atoms to explore

Isoalchorneine

Guanidine alkaloidNitrogen-containing compounds with potent pharmacological effects

Representative pattern: C₉H₇N₂O

Atoms

Nitrogen

Carbon

Hydrogen

Oxygen

Related Compounds (Guanidine alkaloid)

Alchorneine(1)

Live Research

Open on PubMed

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare practitioner before using any herbal product.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This content is for educational purposes only and is not a substitute for professional medical advice.