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Xanthones (Garcinia-type)
In vitroMechanism of Action
Intercalate into DNA of microbial pathogens disrupting replication; inhibit Plasmodium falciparum haem polymerisation (antimalarial mechanism); exhibit antiviral activity by blocking viral RNA-dependent RNA polymerase in vitro.
Research Notes
Bitter KolaAfrican
Garcinia xanthones demonstrate broad in vitro antimicrobial and antiparasitic activity. Their bioavailability in human subjects has not been extensively characterised; ethnopharmacological data support traditional antimalarial and antiinfective use pending clinical validation.
Found In 1 Herb
3D Molecular Structure
Xanthone (oxygenated heterocyclic)
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Xanthones (Garcinia-type)
Xanthone (oxygenated heterocyclic)Bioactive phytochemical with therapeutic properties
Representative pattern: C₄H₂NO
Atoms
Carbon
Oxygen
Nitrogen
Hydrogen
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