Vitexin-2′′-O-Rhamnoside

Preliminary

Flavone-C-glycoside (apigenin diglycoside)

Mechanism of Action

Coronary vasodilation via endothelial nitric oxide synthase (eNOS) upregulation and calcium channel modulation; inhibits cAMP phosphodiesterase; antioxidant; inhibits foam cell formation in atherogenesis

Research Notes

Shan Zha (山楂)TCM

Vitexin rhamnoside demonstrates significant vasodilatory effects in isolated coronary artery preparations and in vivo coronary blood flow models. Pharmacokinetic studies confirm systemic absorption and cardiac tissue distribution. Considered one of the primary cardioprotective compounds alongside OPCs in hawthorn extracts.

Found In 1 Herb

Shan Zha (山楂)

TCM

3D Molecular Structure

Flavone-C-glycoside (apigenin diglycoside)

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Vitexin-2′′-O-Rhamnoside

Flavone-C-glycoside (apigenin diglycoside)Sugar-bound molecules that control drug release in the body

Representative pattern: C₁₅H₁₀O₃

Atoms

Carbon

Oxygen

Live Research

Open on PubMed

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