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Tetrahydropalmatine (THP / dl-THP)
Clinical trialMechanism of Action
Dopamine D1/D2 receptor antagonist, sedative-analgesic, anxiolytic, muscle relaxant, anti-addictive (reduces drug-seeking behavior)
Research Notes
Corydalis (Yan Hu Suo)Western
Analgesic effect confirmed in multiple pain models — effective against visceral, inflammatory, and neuropathic pain. Approved as analgesic drug in China (Rotundine). Anti-addictive effects in cocaine and methamphetamine models.
Found In 1 Herb
3D Molecular Structure
Isoquinoline alkaloid (protoberberine type)
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Tetrahydropalmatine (THP / dl-THP)
Isoquinoline alkaloid (protoberberine type)Nitrogen-containing compounds with potent pharmacological effects
Representative pattern: C₉H₇N₂O
Atoms
Nitrogen
Carbon
Hydrogen
Oxygen
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