SX-fraction

Clinical trial

Mechanism of Action

Enhances insulin receptor sensitivity and promotes GLUT-4 translocation to the cell membrane in skeletal muscle and adipose tissue. Inhibits alpha-glucosidase activity, slowing postprandial glucose absorption. May upregulate hepatic glycogen synthase, promoting glucose storage. Also inhibits the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1), potentially reducing cortisol-mediated insulin resistance.

Research Notes

MaitakeMushroom

Konno et al. (2001) published an open-label pilot study in which type 2 diabetes patients receiving SX-fraction (72 mg/day for 12 weeks) showed significant reductions in fasting blood glucose, HbA1c, and triglycerides compared to baseline. Kubo et al. (1994) demonstrated enhanced insulin sensitivity in KK-Ay diabetic mice fed Maitake powder. Talpur et al. (2002) confirmed hypoglycemic effects in spontaneously hypertensive/diabetic rats. Additional human RCT data remains limited.

Found In 1 Herb

Maitake

Mushroom

3D Molecular Structure

Glycoprotein extract

Drag to rotate · Click atoms to explore

SX-fraction

Glycoprotein extractBioactive phytochemical with therapeutic properties

Representative pattern: C₄H₂NO

Atoms

Carbon

Oxygen

Nitrogen

Hydrogen

Live Research

Open on PubMed

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