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Stigmasterol

Preliminary

Mechanism of Action

Competitively inhibits intestinal absorption of cholesterol via NPC1L1 transporter blockade. Exerts anti-inflammatory effects through PPARγ agonism. In reproductive biology, modulates sperm plasma membrane fluidity critical for capacitation.

Research Notes

Safed MusliAyurvedic

2 g/day plant sterols reduce LDL-cholesterol by 8–15% in controlled trials. Anti-inflammatory effects demonstrated in carrageenan-induced arthritis rodent models with IC50 values for COX-2 inhibition in the 20–40 μM range.

Found In 1 Herb

3D Molecular Structure

Phytosterol
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Stigmasterol

PhytosterolBioactive phytochemical with therapeutic properties

Representative pattern: C₄H₂NO

Atoms
Carbon
Oxygen
Nitrogen
Hydrogen

Related Compounds (Phytosterol)

Live Research

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