Stachyose

Moderate

Mechanism of Action

Stachyose acts as a prebiotic that selectively promotes the growth of Bifidobacterium and Lactobacillus species in the colon. It resists digestion by human α-galactosidases and reaches the large intestine intact, where it is fermented to short-chain fatty acids (SCFAs) including butyrate, propionate, and acetate. These SCFAs nourish colonocytes, lower colonic pH to inhibit pathogenic bacteria, and modulate mucosal immune function by promoting regulatory T-cell differentiation.

Research Notes

Rehmannia (Di Huang)TCM

A clinical study in 60 constipation patients showed that stachyose supplementation (5 g/day for 14 days) significantly increased fecal Bifidobacterium counts and improved bowel frequency compared to placebo (Chen et al., World J Gastroenterol, 2014). In vitro fermentation models confirmed selective stimulation of beneficial anaerobes over Clostridium and E. coli species.

Found In 1 Herb

Rehmannia (Di Huang)

TCM

3D Molecular Structure

Oligosaccharide (tetrasaccharide)

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Stachyose

Oligosaccharide (tetrasaccharide)Bioactive phytochemical with therapeutic properties

Representative pattern: C₄H₂NO

Atoms

Carbon

Oxygen

Nitrogen

Hydrogen

Live Research

Open on PubMed

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