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Spirostanol Saponins (Borivilianosides)
ModerateMechanism of Action
Stimulate Leydig cell testosterone secretion by upregulating StAR protein expression and CYP17A1 enzyme activity in testicular tissue, enhancing cholesterol transport into the mitochondrial matrix and increasing androgen biosynthesis. Promote Sertoli cell proliferation and spermatogonial differentiation via GDNF receptor pathway activation.
Research Notes
Safed MusliAyurvedic
A double-blind RCT (n=60 oligospermic men) demonstrated 5 g/day Safed Musli root powder for 90 days produced significant increases in total sperm count (42.3%), sperm motility (27.8%), and serum testosterone (18.5%) versus placebo.
Found In 1 Herb
3D Molecular Structure
Steroidal saponins (spirostanol glycosides)
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Spirostanol Saponins (Borivilianosides)
Steroidal saponins (spirostanol glycosides)Sugar-bound molecules that control drug release in the body
Representative pattern: C₂₁H₃₀O₂
Atoms
Carbon
Oxygen
Live Research
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