Sinapic acid

In vitro / Animal

Mechanism of Action

Anti-inflammatory and antioxidant phenolic; contributes to the herb's anti-rheumatic reputation

Potent antioxidant via direct radical scavenging and iron chelation; suppresses PGE2 and TNF-α production from activated macrophages via COX-2 and NF-κB inhibition; reversible MAO-A and MAO-B inhibitor at µM concentrations modulating monoamine catabolism with antidepressant-adjacent effects; GABA-A modulation at higher concentrations producing anxiolytic effects in rodent models

Research Notes

Garden CressWestern

Documented anti-inflammatory and antioxidant activity in preclinical studies.

Mustard SeedWestern

Multiple antioxidant assays (DPPH, ABTS, ORAC) consistently rank sinapic acid among the most potent hydroxycinnamic acid antioxidants. MAO inhibitory activity confirmed in enzyme kinetic assays; anxiolytic effects demonstrated in rodent elevated plus-maze and open-field tests. Neuroprotective effects against oxidative neuronal injury validated in cell and animal models. Human clinical evidence absent.

Found In 2 Herbs

Garden Cress

Western

Mustard Seed

Western

3D Molecular Structure

Hydroxycinnamic acid

Drag to rotate · Click atoms to explore

Sinapic acid

Hydroxycinnamic acidBioactive phytochemical with therapeutic properties

Representative pattern: C₇H₆O₃

Atoms

Carbon

Oxygen

Hydrogen

Related Compounds (Hydroxycinnamic acid)

Caffeic acid(2)Caffeic acid & Chlorogenic acid(1)Caffeic acid derivatives(4)Ferulic acid(2)Phenolic acids (ferulic acid, p-coumaric acid)(1)

Live Research

Open on PubMed

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