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Sinapic acid
In vitro / AnimalMechanism of Action
Anti-inflammatory and antioxidant phenolic; contributes to the herb's anti-rheumatic reputation
Potent antioxidant via direct radical scavenging and iron chelation; suppresses PGE2 and TNF-α production from activated macrophages via COX-2 and NF-κB inhibition; reversible MAO-A and MAO-B inhibitor at µM concentrations modulating monoamine catabolism with antidepressant-adjacent effects; GABA-A modulation at higher concentrations producing anxiolytic effects in rodent models
Research Notes
Garden CressWestern
Documented anti-inflammatory and antioxidant activity in preclinical studies.
Mustard SeedWestern
Multiple antioxidant assays (DPPH, ABTS, ORAC) consistently rank sinapic acid among the most potent hydroxycinnamic acid antioxidants. MAO inhibitory activity confirmed in enzyme kinetic assays; anxiolytic effects demonstrated in rodent elevated plus-maze and open-field tests. Neuroprotective effects against oxidative neuronal injury validated in cell and animal models. Human clinical evidence absent.
Found In 2 Herbs
3D Molecular Structure
Hydroxycinnamic acid
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Sinapic acid
Hydroxycinnamic acidBioactive phytochemical with therapeutic properties
Representative pattern: C₇H₆O₃
Atoms
Carbon
Oxygen
Hydrogen
Related Compounds (Hydroxycinnamic acid)
Live Research
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