Sennosides A and B

Clinical trial

Mechanism of Action

Dianthrone glycosides converted by colonic bacteria to rhein anthrone, which stimulates peristalsis and fluid secretion into the large intestine

Research Notes

American SennaWestern

Sennosides are among the most well-studied botanical laxatives. Clinical trials confirm reliable cathartic effect within 6–12 hours of oral dosing. Mechanism of action is well characterised through bacterial hydrolysis to active rhein anthrone.

Found In 1 Herb

American Senna

Western

3D Molecular Structure

Anthraquinone glycoside

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Sennosides A and B

Anthraquinone glycosideSugar-bound molecules that control drug release in the body

Representative pattern: C₁₁H₁₄O₆

Atoms

Carbon

Oxygen

Related Compounds (Anthraquinone glycoside)

Cascarosides A/B(1)Frangulin A(1)Frangulin B(1)Sennosides A & B(1)Sennosides A/B(1)

Live Research

Open on PubMed

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