Salicin
Clinical trialMechanism of Action
Research Notes
Salicin undergoes gut bacterial hydrolysis to release salicylic acid. Animal models show anti-inflammatory activity comparable to low-dose aspirin without gastric ulceration risk.
Poplar bark contains salicin at concentrations (4-10%) comparable to white willow, providing similar anti-inflammatory and analgesic effects. Traditional use supports efficacy for arthritis and joint pain; clinical trials show efficacy in musculoskeletal conditions.
Salicin from white willow bark demonstrates anti-inflammatory and analgesic effects comparable to acetylsalicylic acid, though with slower onset due to metabolic conversion requirements. Multiple clinical trials show efficacy for musculoskeletal pain, particularly lower back pain and osteoarthritis. Bioavailability improved when consumed with food.
Found In 3 Herbs
3D Molecular Structure
Salicin
Representative pattern: C₁₁H₁₄O₆
Related Compounds (Phenolic glycoside)
Live Research
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