Rooperol

Preliminary

Mechanism of Action

Potent antioxidant and free radical scavenger via catechol electron donation; inhibits leukotriene B4 synthesis (5-LOX pathway) and prostaglandin E2 production (COX-2), mediating anti-inflammatory effects; stimulates natural killer (NK) cell cytotoxicity and T-lymphocyte proliferation through upregulation of interleukin-2 and interferon-gamma; induces apoptosis in tumour cell lines via mitochondrial pathway and caspase-3 activation.

Research Notes

African PotatoAfrican

In vitro and ex vivo studies demonstrate significant immunostimulatory activity including enhanced NK-cell killing of tumour targets and lymphocyte proliferation. Antitumour activity confirmed in multiple cancer cell lines (breast, colon, prostate). Human clinical trial data remain limited to small pilot studies; no large RCTs establishing clinical efficacy for any indication have been completed. The immunostimulatory effect is pharmacologically relevant to the drug interaction profile with immunosuppressants.

Found In 1 Herb

African Potato

African

3D Molecular Structure

Catechol norlignan (active metabolite)

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Rooperol

Catechol norlignan (active metabolite)Plant polyphenols with antioxidant and estrogenic activity

Representative pattern: C₄H₂NO

Atoms

Carbon

Oxygen

Nitrogen

Hydrogen

Live Research

Open on PubMed

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