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Mechanism of Action

GABA receptor modulation; opioid receptor interaction; anti-inflammatory through NF-κB inhibition
Secondary alkaloid with antispasmodic and weak sedative activity; also found in greater celandine and California poppy

Research Notes

Protopine is a secondary alkaloid in California poppy with sedative-analgesic and anxiolytic properties. Clinical evidence shows efficacy for anxiety and mild pain; mechanism involves GABAergic and opioid system modulation.

FumitoryWestern

Well-characterised isoquinoline alkaloid found across multiple Papaveraceae species. Antispasmodic and mild sedative activity demonstrated in pharmacological studies.

Found In 2 Herbs

3D Molecular Structure

Isoquinoline alkaloid (benzylisoquinoline derivative, protoberberine-type)
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Protopine

Isoquinoline alkaloid (benzylisoquinoline derivative, protoberberine-type)Nitrogen-containing compounds with potent pharmacological effects

Representative pattern: C₉H₇N₂O

Atoms
Nitrogen
Carbon
Hydrogen
Oxygen

Live Research

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