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Protoanemonin
In vitro / AnimalMechanism of Action
Potent vesicant and irritant; responsible for counter-irritant and toxic effects; destroyed by drying
Toxic vesicant present in fresh plant only; destroyed by drying. Responsible for fresh-plant toxicity.
Vesicant (causes blistering); antimicrobial; toxic — converts to anemonin on drying
Research Notes
ButtercupWestern
Potent vesicant responsible for both therapeutic rubefacient activity and toxicity. Destroyed by drying.
Lesser CelandineWestern
Toxic vesicant destroyed by drying; responsible for the contraindication against fresh-plant internal use.
PulsatillaWestern
Potent skin irritant and vesicant in fresh plant; antimicrobial activity; decomposes to less toxic anemonin upon drying
Found In 3 Herbs
3D Molecular Structure
Lactone
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Protoanemonin
LactoneCyclic esters with diverse pharmacological activities
Representative pattern: C₂₁H₃₀O₂
Atoms
Carbon
Oxygen
Live Research
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