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Polysaccharides (CGPs)

Preliminary
Heteropolysaccharide

Mechanism of Action

C. guangdongensis polysaccharides (molecular weights ranging from 5.21 × 10³ to 1.28 × 10⁶ Da) activate innate immune cells through pattern recognition receptor engagement including dectin-1, TLR-2, and TLR-4. Downstream signaling promotes macrophage activation, cytokine production (IL-2, TNF-α, IFN-γ), and natural killer cell activity. Anti-fatigue mechanism involves reducing blood lactic acid accumulation and enhancing hepatic glycogen storage, thereby delaying exercise-induced metabolic acidosis.

Research Notes

Cordyceps guangdongensisMushroom

A key study published in Pharmaceutical Biology (2013) demonstrated that C. guangdongensis polysaccharide extracts extended swimming time to exhaustion by 2.66-fold in mice compared to controls, with significant reduction in blood lactic acid. Hot water extracts (polysaccharide content 6.92%) showed anti-inflammatory activity against chronic bronchitis in tobacco smoke-exposed rats (published in Food & Function, 2014). All studies are preclinical; no human clinical trials specific to C. guangdongensis polysaccharides have been published.

Found In 1 Herb

Cordyceps guangdongensis

Cordyceps guangdongensis

Mushroom

3D Molecular Structure

Heteropolysaccharide
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Polysaccharides (CGPs)

HeteropolysaccharideComplex carbohydrate polymers that modulate immune response

Representative pattern: (C₆H₁₀O₅)ₙ

Atoms
Carbon
Oxygen

Related Compounds (Heteropolysaccharide)

Asparagus polysaccharides(1)Codonopsis polysaccharides(1)Polygonatum polysaccharides(1)Polysaccharides (arabinogalactans)(1)Pseudostellaria polysaccharides(1)

Live Research

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