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Piperine
Meta-analysisMechanism of Action
CYP3A4, CYP2D6, CYP1A2, P-glycoprotein inhibition; thermogenic via TRPV1 activation; increases GI blood flow and absorption
CYP3A4/CYP2D6 inhibition; P-glycoprotein inhibition; thermogenic
Bioavailability enhancement via CYP450 and P-gp inhibition; thermogenic
Research Notes
Black Pepper (Maricha)Ayurvedic
Most studied herbal bioenhancer. Increases curcumin bioavailability ~2000%. Enhances absorption of multiple drugs.
PippaliAyurvedic
Increases bioavailability of curcumin by 2000%; enhances rifampicin, theophylline absorption
TrikatuAyurvedic
Increases absorption of curcumin, resveratrol and many pharmaceuticals
Found In 3 Herbs
3D Molecular Structure
Piperidine alkaloid
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Piperine
Piperidine alkaloidNitrogen-containing compounds with potent pharmacological effects
Representative pattern: C₉H₇N₂O
Atoms
Nitrogen
Carbon
Hydrogen
Oxygen
Related Compounds (Piperidine alkaloid)
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