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Mechanism of Action

Inhibits leukotriene synthesis via 5-lipoxygenase pathway; reduces TNF-α and IL-1β in inflammatory cells

Research Notes

ButterburWestern

Petasin is the primary anti-inflammatory sesquiterpene in butterbur, with clinical evidence for migraine prophylaxis and allergy symptom reduction. Demonstrates efficacy in reducing joint inflammation and musculoskeletal pain through leukotriene pathway inhibition.

Found In 1 Herb

3D Molecular Structure

Sesquiterpene ester (eremophilane derivative)
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Petasin

Sesquiterpene ester (eremophilane derivative)Aromatic plant metabolites with anti-inflammatory properties

Representative pattern: C₁₀H₁₆O

Atoms
Carbon
Oxygen
Hydrogen

Live Research

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