p-Hydroxybenzyl isothiocyanate (p-HBITC)

In vitro

Aromatic isothiocyanate / glucosinolate metabolite

Mechanism of Action

Less volatile than AITC — produces milder rubefaction with less respiratory irritation; inhibits alpha-glucosidase contributing to postprandial glucose attenuation; antimicrobial via membrane disruption; anti-inflammatory through iNOS and NF-κB inhibition; antifungal activity against Candida albicans and dermatophytes

Research Notes

Mustard SeedWestern

Alpha-glucosidase inhibitory activity confirmed in enzyme assays (IC50 ~85 µM). Antimicrobial activity against food pathogens documented for white mustard preparations. Anti-inflammatory mechanistic studies validated in macrophage activation models. Milder dermal and mucosal effects than AITC make white mustard safer for internal applications.

Found In 1 Herb

Mustard Seed

Western

3D Molecular Structure

Aromatic isothiocyanate / glucosinolate metabolite

Drag to rotate · Click atoms to explore

p-Hydroxybenzyl isothiocyanate (p-HBITC)

Aromatic isothiocyanate / glucosinolate metaboliteBioactive phytochemical with therapeutic properties

Representative pattern: C₄H₂NO

Atoms

Carbon

Oxygen

Nitrogen

Hydrogen

Live Research

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