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Officinalic acid
In vitroMechanism of Action
A structurally unique lanostane-type triterpenoid identified specifically from Fomitopsis officinalis with inhibitory activity against influenza A (H1N1) viral replication in ex vivo assays; precise molecular target has not been fully characterised, though viral RNA polymerase inhibition has been proposed as a mechanism based on structural modelling studies.
Research Notes
AgarikonMushroom
Officinalic acid represents one of the chemotaxonomically distinctive compounds of Fomitopsis officinalis relative to related Fomitopsis species. It was identified in bioactivity-guided fractionation studies of Agarikon extracts for antiviral properties. Preliminary antiviral data are from ex vivo cell culture models only; no in vivo or clinical data are available. Its status as a potential novel antiviral scaffold has attracted limited but growing interest.
Found In 1 Herb
3D Molecular Structure
Lanostane triterpenoid (Agarikon-specific)
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Officinalic acid
Lanostane triterpenoid (Agarikon-specific)Modified terpenes with diverse biological activities
Representative pattern: C₁₀H₁₆O
Atoms
Carbon
Oxygen
Hydrogen
Live Research
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