Loading…
Back to Compound Explorer
Nuciferine
In vitro / AnimalMechanism of Action
Dopamine receptor antagonist (D1 and D2); sigma-1 receptor interaction; potential GABA modulation
Dopamine D2 receptor antagonism; 5-HT2 modulation; lipase inhibition
Research Notes
Blue LotusWestern
Primary psychoactive alkaloid in Nymphaea caerulea. In vitro studies demonstrate dopamine antagonism in low micromolar concentrations. Animal models show CNS depression and anxiolytic-like effects. Research suggests potential antipsychotic properties (via dopamine antagonism) and neuroprotective effects (via sigma-1 activation), but human pharmacokinetics and bioavailability poorly characterized. Euphoric effects observed in traditional use may result from dopamine antagonism at low doses creating distinctive psychopharmacological state.
LotusAyurvedic
Anti-obesity and sedative effects in animal models; antiarrhythmic potential
Found In 2 Herbs
3D Molecular Structure
Isoquinoline alkaloid - aporphine-type
Drag to rotate · Click atoms to explore
Nuciferine
Isoquinoline alkaloid - aporphine-typeNitrogen-containing compounds with potent pharmacological effects
Representative pattern: C₉H₇N₂O
Atoms
Nitrogen
Carbon
Hydrogen
Oxygen
Related Compounds (Isoquinoline alkaloid - aporphine-type)
Live Research
This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare practitioner before using any herbal product.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This content is for educational purposes only and is not a substitute for professional medical advice.