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The complexity of bilberry's anthocyanin profile (15+ compounds vs. 2–4 in blackcurrant) is thought to contribute to its exceptionally broad pharmacological activity spectrum. Animal models demonstrate dose-dependent improvements in retinal perfusion and reduction of oxidative stress markers in diabetic retinopathy models. Human bioavailability studies show anthocyanin peak plasma concentrations 1–2 hours post-ingestion with urinary excretion reflecting renal tubular reabsorption of intact glycosides.
Representative pattern: C₁₅H₁₀O₃
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