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Myristicin
Clinical trialMechanism of Action
Weak MAO inhibition; metabolised to MMDA-like amphetamine derivative (3-methoxy-4,5-methylenedioxyamphetamine); serotonergic activity; hepatotoxic at high dose
Inhibits monoamine oxidase (MAO), increasing catecholamine availability; stimulates renal blood flow and glomerular filtration; hepatoprotective through glutathione S-transferase induction
Psychoactive phenylpropanoid found in parsnip seed essential oil; contributes to carminative effect
Research Notes
Nutmeg (Jatiphala)Ayurvedic
Responsible for psychoactive effects of nutmeg intoxication. MAO inhibitory and serotonergic activity explain antidepressant potential at low doses and toxicity at high doses.
ParsleyWestern
Myristicin demonstrates MAO inhibitory activity and hepatoprotective effects in animal models. It is the primary constituent responsible for parsley's diuretic action. Large doses can be psychoactive (as seen with nutmeg intoxication). Therapeutic doses in parsley are well below psychoactive thresholds.
Wild ParsnipWestern
Carminative phenylpropanoid also found in nutmeg. Preclinical evidence for antioxidant and insecticidal activity.
Found In 3 Herbs
3D Molecular Structure
Phenylpropanoid (allylbenzene)
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Myristicin
Phenylpropanoid (allylbenzene)Bioactive phytochemical with therapeutic properties
Representative pattern: C₇H₆O₃
Atoms
Carbon
Oxygen
Hydrogen
Live Research
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