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Mirabilis Antimicrobial Peptides (MAPs)
In vitroMechanism of Action
MAPs disrupt microbial cell membranes through electrostatic interaction with phospholipid bilayers, leading to pore formation and cell lysis. They show broad-spectrum activity against both Gram-positive and Gram-negative bacteria as well as certain fungi.
Research Notes
ClavilliaSouth American
In vitro studies have demonstrated that MAPs from M. jalapa roots exhibit significant antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans at low micromolar concentrations. A 2009 study in Peptides journal characterized two novel MAPs with IC50 values in the 2–10 μM range against multiple pathogens.
Found In 1 Herb
3D Molecular Structure
Antimicrobial peptide
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Mirabilis Antimicrobial Peptides (MAPs)
Antimicrobial peptideBioactive phytochemical with therapeutic properties
Representative pattern: C₄H₂NO
Atoms
Carbon
Oxygen
Nitrogen
Hydrogen
Live Research
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