Mirabilis Antimicrobial Peptides (MAPs)

In vitro

Mechanism of Action

MAPs disrupt microbial cell membranes through electrostatic interaction with phospholipid bilayers, leading to pore formation and cell lysis. They show broad-spectrum activity against both Gram-positive and Gram-negative bacteria as well as certain fungi.

Research Notes

ClavilliaSouth American

In vitro studies have demonstrated that MAPs from M. jalapa roots exhibit significant antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans at low micromolar concentrations. A 2009 study in Peptides journal characterized two novel MAPs with IC50 values in the 2–10 μM range against multiple pathogens.

Found In 1 Herb

Clavillia

South American

3D Molecular Structure

Antimicrobial peptide

Drag to rotate · Click atoms to explore

Mirabilis Antimicrobial Peptides (MAPs)

Antimicrobial peptideBioactive phytochemical with therapeutic properties

Representative pattern: C₄H₂NO

Atoms

Carbon

Oxygen

Nitrogen

Hydrogen

Live Research

Open on PubMed

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