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Marsdenine and analogues

In vitro

Mechanism of Action

Cytotoxic activity against human cancer cell lines including gastric adenocarcinoma; disrupts microtubule dynamics and inhibits cell cycle progression at G2/M phase

Research Notes

CondurangoSouth American

Preliminary in vitro cytotoxicity demonstrated against gastric adenocarcinoma cell lines. Mechanism involves microtubule disruption analogous to vinca alkaloids. No human clinical trials conducted.

Found In 1 Herb

3D Molecular Structure

Steroidal Alkaloid
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Marsdenine and analogues

Steroidal AlkaloidNitrogen-containing compounds with potent pharmacological effects

Representative pattern: C₉H₇N₂O

Atoms
Nitrogen
Carbon
Hydrogen
Oxygen

Related Compounds (Steroidal Alkaloid)

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