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Isorhamnetin

In vitro / Animal
Flavonol (O-methylated quercetin derivative)

Mechanism of Action

Inhibits NF-κB-mediated pro-inflammatory cytokine expression; antioxidant via flavonoid radical stabilisation; hepatoprotective through Nrf2/HO-1 pathway upregulation; exhibits mild antiproliferative activity in hepatic stellate cell models relevant to fibrosis prevention.
Anti-inflammatory; cardioprotective through endothelial function improvement; anti-atherogenic

Research Notes

BoldoSouth American

Isorhamnetin contributes to boldo's hepatoprotective and anti-inflammatory profile, with in vitro data showing synergistic activity with boldine in reducing hepatic oxidative injury. Isorhamnetin is well characterised across multiple plant sources, with a consistent body of preclinical anti-inflammatory evidence.

Sea BuckthornAyurvedic

Isorhamnetin from sea buckthorn shows cardiovascular protective effects including improved endothelial function and reduced LDL oxidation in preclinical models.

Found In 2 Herbs

Boldo

Boldo

South American
Sea Buckthorn

Sea Buckthorn

Ayurvedic

3D Molecular Structure

Flavonol (O-methylated quercetin derivative)
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Isorhamnetin

Flavonol (O-methylated quercetin derivative)Bioactive phytochemical with therapeutic properties

Representative pattern: C₁₅H₁₀O₃

Atoms
Carbon
Oxygen

Live Research

Open on PubMed

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare practitioner before using any herbal product.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This content is for educational purposes only and is not a substitute for professional medical advice.