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Isomenthone
PreliminaryMechanism of Action
Isomenthone is a less toxic monoterpene present in pennyroyal essential oil that contributes to the herb's carminative and antispasmodic properties. It modulates gastrointestinal smooth-muscle calcium channels, reducing spasm, and has mild antimicrobial activity against gram-positive bacteria.
Research Notes
PennyroyalWestern
Isomenthone has been identified in pennyroyal oil GC-MS analyses at 2–20% depending on chemotype. In vitro studies show antispasmodic effects on isolated guinea pig ileum comparable to other mint monoterpenes. No human clinical trials exist for isolated isomenthone.
Found In 1 Herb
3D Molecular Structure
Monoterpene ketone
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Isomenthone
Monoterpene ketoneAromatic plant metabolites with anti-inflammatory properties
Representative pattern: C₁₀H₁₆O
Atoms
Carbon
Oxygen
Hydrogen
Related Compounds (Monoterpene ketone)
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