Interfungin A

Preliminary

Polyphenol (highly oxygenated hispidin dimer)

Mechanism of Action

Highly oxygenated and unsaturated hispidin-class metabolite with potent free-radical scavenging activity against superoxide radical cation, ABTS radical anion, and DPPH radical. The interfungin series (A, B, C) represents structural diversification within the hispidin compound class found across Inonotus and Phellinus genera, providing multi-target antioxidant defense and emerging evidence of anti-inflammatory and cytoprotective activity.

Research Notes

Black Hoof MushroomMushroom

Interfungins A, B, and C were isolated and characterized from Phellinus species by Zhu et al. (Bioorganic & Medicinal Chemistry, 2008), demonstrating significant free-radical scavenging activity in DPPH, ABTS, and superoxide assays. Interfungin A was subsequently identified in cultivated P. baumii alongside baumin, davallialactone, hispidin, and other styrylpyrones. The compounds represent unique chemotaxonomic markers linking the Inonotus-Phellinus medicinal mushroom complex.

Found In 1 Herb

Black Hoof Mushroom

Mushroom

3D Molecular Structure

Polyphenol (highly oxygenated hispidin dimer)

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Interfungin A

Polyphenol (highly oxygenated hispidin dimer)Simple aromatic compounds with antimicrobial properties

Representative pattern: C₇H₆O₃

Atoms

Carbon

Oxygen

Hydrogen

Live Research

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