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Ibotenic acid

Well-established neurochemistry; human toxicology primarily from poisoning cases

Mechanism of Action

Glutamate receptor agonist (ionotropic and metabotropic); converted to muscimol via decarboxylation during drying or stomach acid exposure

Research Notes

Fly AgaricMushroom

Primary neurotoxic compound in fresh mushrooms; responsible for excitotoxicity, convulsions, and acute toxicity symptoms. Undergoes metabolic conversion to muscimol, the psychoactive metabolite. Research indicates dose-dependent neurotoxicity with LD50 estimates around 38 mg/kg in animal models.

Found In 1 Herb

3D Molecular Structure

Isoxazole alkaloid
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Ibotenic acid

Isoxazole alkaloidNitrogen-containing compounds with potent pharmacological effects

Representative pattern: C₉H₇N₂O

Atoms
Nitrogen
Carbon
Hydrogen
Oxygen

Related Compounds (Isoxazole alkaloid)

Live Research

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