Hederacoside C

Clinical trial

Bisdesmosidic triterpene saponin (oleanane-type)

Mechanism of Action

Prodrug that is hydrolyzed in the GI tract and liver to alpha-hederin (the active metabolite); the intact molecule has low bioactivity but serves as a stable delivery form for the active aglycone

Research Notes

Ivy LeafWestern

Hederacoside C is the most abundant saponin in ivy leaf and is used as the primary standardization marker for commercial ivy leaf extracts (typically standardized to 10-20% hederacoside C). Pharmacokinetic studies confirm its rapid conversion to alpha-hederin following oral administration. The prodrug relationship was elucidated by research at the University of Bonn.

Found In 1 Herb

Ivy Leaf

Western

3D Molecular Structure

Bisdesmosidic triterpene saponin (oleanane-type)

Drag to rotate · Click atoms to explore

Hederacoside C

Bisdesmosidic triterpene saponin (oleanane-type)Aromatic plant metabolites with anti-inflammatory properties

Representative pattern: C₁₁H₁₄O₆

Atoms

Carbon

Oxygen

Live Research

Open on PubMed

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare practitioner before using any herbal product.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This content is for educational purposes only and is not a substitute for professional medical advice.