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Mechanism of Action

Complementary iridoid contributing to overall anti-inflammatory effect; synergistic with harpagoside
Bitter anti-inflammatory glycoside contributing to wound-healing and antispasmodic activity

Research Notes

Harpagide is a minor iridoid constituent that enhances the anti-inflammatory profile of devil's claw through additive NF-κB inhibition and TNF-α suppression. Present in lower concentrations than harpagoside but contributes meaningfully to overall efficacy.

Iridoid glycoside with documented anti-inflammatory and analgesic activity in preclinical studies.

Found In 2 Herbs

3D Molecular Structure

Iridoid glycoside (monoterpene derivative)
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Harpagide

Iridoid glycoside (monoterpene derivative)Aromatic plant metabolites with anti-inflammatory properties

Representative pattern: C₁₁H₁₄O₆

Atoms
Carbon
Oxygen

Live Research

Open on PubMed

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