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Gymnemasaponins I–V
PreliminaryMechanism of Action
Reduce hepatic de novo lipogenesis by downregulating SREBP-1c. Inhibit pancreatic lipase activity. Exhibit hepatoprotective activity through Nrf2/ARE pathway activation.
Research Notes
Gymnema SylvestreAyurvedic
In vivo anti-hyperlipidemic effects demonstrated in high-fat diet-fed rats with significant reductions in total cholesterol (22–28%), triglycerides (19–26%), and LDL-C (24–31%).
Found In 1 Herb
3D Molecular Structure
Triterpenoid saponins (oleanolic acid and bayogenin glycosides)
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Gymnemasaponins I–V
Triterpenoid saponins (oleanolic acid and bayogenin glycosides)Modified terpenes with diverse biological activities
Representative pattern: C₁₁H₁₄O₆
Atoms
Carbon
Oxygen
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