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Griffonin
In vitroMechanism of Action
Binds N-acetylglucosamine and N-acetylneuraminic acid residues on cell surface glycoproteins; exhibits agglutinating activity and has been investigated for selective binding to tumour-associated carbohydrate antigens.
Exhibits cytotoxic activity against certain tumour cell lines in vitro through induction of apoptosis; also demonstrates antimicrobial properties against Gram-positive bacteria via membrane disruption.
Research Notes
GriffoniaAfrican
Predominantly explored in in vitro oncology models; no clinical human data for therapeutic use of isolated griffonin. Research interest is early-stage and primarily academic.
GriffoniaAfrican
Preclinical in vitro data suggest antiproliferative activity in cancer cell lines including HeLa and MCF-7. Antimicrobial effects against Staphylococcus aureus and Streptococcus spp. have been documented; no human clinical data are available.
Found In 2 Herbs
3D Molecular Structure
Lectin (glycoprotein)
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Griffonin
Lectin (glycoprotein)Bioactive phytochemical with therapeutic properties
Representative pattern: C₄H₂NO
Atoms
Carbon
Oxygen
Nitrogen
Hydrogen
Live Research
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