Griffonin

In vitro

Mechanism of Action

Binds N-acetylglucosamine and N-acetylneuraminic acid residues on cell surface glycoproteins; exhibits agglutinating activity and has been investigated for selective binding to tumour-associated carbohydrate antigens.

Exhibits cytotoxic activity against certain tumour cell lines in vitro through induction of apoptosis; also demonstrates antimicrobial properties against Gram-positive bacteria via membrane disruption.

Research Notes

GriffoniaAfrican

Predominantly explored in in vitro oncology models; no clinical human data for therapeutic use of isolated griffonin. Research interest is early-stage and primarily academic.

GriffoniaAfrican

Preclinical in vitro data suggest antiproliferative activity in cancer cell lines including HeLa and MCF-7. Antimicrobial effects against Staphylococcus aureus and Streptococcus spp. have been documented; no human clinical data are available.

Found In 2 Herbs

Griffonia

African

Griffonia

African

3D Molecular Structure

Lectin (glycoprotein)

Drag to rotate · Click atoms to explore

Griffonin

Lectin (glycoprotein)Bioactive phytochemical with therapeutic properties

Representative pattern: C₄H₂NO

Atoms

Carbon

Oxygen

Nitrogen

Hydrogen

Live Research

Open on PubMed

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