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Gallic acid

Clinical trial

Mechanism of Action

Astringent and antimicrobial; precipitates proteins on mucosal surfaces, reducing inflammation
Antimicrobial and antioxidant; released on hydrolysis of gallotannins
Antioxidant (free radical scavenging, metal chelation); anti-inflammatory via COX-2 and iNOS inhibition; antimicrobial; hepatoprotective
Antioxidant and antimicrobial activity; contributes to overall astringent and anti-inflammatory profile
Antioxidant via free radical scavenging; anti-inflammatory through NF-kB inhibition; neuroprotective
Antioxidant via free radical scavenging; anti-inflammatory via NF-κB inhibition; antimicrobial
Antioxidant and antimicrobial; enhances fibroblast proliferation for wound healing

Research Notes

Gallic acid and related tannins contribute to the astringent and antimicrobial properties of bearberry. High tannin content is responsible for GI side effects, which is why cold maceration is recommended.

Well-characterized antimicrobial and antioxidant.

HaritakiAyurvedic

Well-characterized antioxidant with clinical evidence for hepatoprotection; antimicrobial against both gram-positive and gram-negative bacteria; anti-cancer activity in multiple cell lines

Well-characterized phenolic acid with established antioxidant and antimicrobial properties in preclinical studies.

Gallic acid is a major polyphenol in longan aril. In vitro studies demonstrate potent antioxidant and anti-inflammatory activity.

TriphalaAyurvedic

Potent antioxidant. Contributes to Triphala's GI-protective and antimicrobial effects. Well-characterised.

Gallic acid contributes to witch hazel's antioxidant capacity and antimicrobial spectrum against multiple bacterial strains relevant to wound infection.

Found In 7 Herbs

3D Molecular Structure

Phenolic acid (tannin)
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Gallic acid

Phenolic acid (tannin)Simple aromatic compounds with antimicrobial properties

Representative pattern: C₂₁H₁₈O₅

Atoms
Carbon
Oxygen

Live Research

Open on PubMed

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