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Forskolin

Clinical trial

Mechanism of Action

Adenylyl cyclase activation increasing intracellular cAMP; positive inotropic and chronotropic effects; vasodilation

Research Notes

Forskolin increases cardiac contractility and heart rate through cAMP upregulation with clinical evidence in cardiomyopathy. Reduces blood pressure through vascular smooth muscle relaxation. Primary active diterpene in Coleus.

Found In 1 Herb

3D Molecular Structure

Labdane diterpene
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Forskolin

Labdane diterpeneAromatic plant metabolites with anti-inflammatory properties

Representative pattern: C₁₀H₁₆O

Atoms
Carbon
Oxygen
Hydrogen

Live Research

Open on PubMed

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