Eucalyptin

Eucalyptin is found primarily in leaf extracts rather than in steam-distilled essential oil (as it is non-volatile). In vitro studies by Santos et al. (2012) demonstrated significant anti-inflammatory activity of eucalyptin through dual COX-2/5-LOX inhibition at low micromolar concentrations. Research on E. globulus leaf methanolic extracts has identified eucalyptin as a major contributor to the antioxidant capacity of eucalyptus leaf preparations, though human clinical data specifically attributing effects to eucalyptin are lacking. It represents a pharmacologically relevant compound in traditional leaf tea and tincture preparations.