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Enokipodin
In vitroMechanism of Action
Enokipodins A–D are cuparene-type sesquiterpene compounds with antimicrobial activity against both Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus) and phytopathogenic fungi. The mechanism involves disruption of microbial cell membrane integrity through interaction with ergosterol and other membrane sterols. Enokipodin A also demonstrates mild antioxidant activity through radical scavenging.
Research Notes
Enoki (Medicinal)Mushroom
Ishikawa et al. (2001) isolated and characterized enokipodins A–D from Flammulina velutipes mycelium and demonstrated antimicrobial activity against several test organisms. The cuparene sesquiterpene skeleton is relatively uncommon in basidiomycete fungi. Antioxidant and antimicrobial properties have been confirmed but no clinical studies exist.
Found In 1 Herb
3D Molecular Structure
Sesquiterpene (cuparene-type)
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Enokipodin
Sesquiterpene (cuparene-type)Aromatic plant metabolites with anti-inflammatory properties
Representative pattern: C₁₀H₁₆O
Atoms
Carbon
Oxygen
Hydrogen
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