Emodin

Clinical trial

Mechanism of Action

The principal metabolically active form; stimulates chloride secretion and inhibits water absorption in the colon, promoting laxation

Laxative via stimulation of colonic motility, anti-inflammatory, pro-apoptotic; HEPATOTOXIC in excess

Selective stimulation of colonic smooth muscle contractions; antimicrobial against pathogenic gram-positive bacteria

Research Notes

Alder BuckthornWestern

Extensively studied anthraquinone with well-established mechanism of colonic stimulation.

He Shou Wu (Fo-Ti)TCM

Associated with hepatotoxicity in multiple case reports and systematic reviews. Mechanism involves mitochondrial damage and oxidative stress in hepatocytes. Also demonstrates anti-cancer properties in vitro.

Yellow DockWestern

Emodin demonstrates strong in vitro activity against Clostridium difficile and Staphylococcus aureus. Animal models show increased intestinal transit and improved bowel regularity.

Found In 3 Herbs

3D Molecular Structure

Anthraquinone aglycone

Drag to rotate · Click atoms to explore

Emodin

Anthraquinone aglyconeBioactive phytochemical with therapeutic properties

Representative pattern: C₄H₂NO

Atoms

Carbon

Oxygen

Nitrogen

Hydrogen

Live Research

Open on PubMed

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