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Dehydrocorybulbine (DHCB)
Clinical trialMechanism of Action
D2 dopamine receptor antagonist; monoamine reuptake inhibition (dopamine, serotonin); opioid receptor modulation; analgesic without respiratory depression
Research Notes
Corydalis (Yan Hu Suo)Western
DHCB is the primary alkaloid in corydalis with clinical evidence for moderate pain relief and migraine prevention in Chinese traditional medicine. Shows analgesic efficacy comparable to some weak opioids without respiratory depression or high addiction risk; mechanisms primarily dopaminergic and monoaminergic.
Found In 1 Herb
3D Molecular Structure
Isoquinoline alkaloid (benzylisoquinoline derivative)
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Dehydrocorybulbine (DHCB)
Isoquinoline alkaloid (benzylisoquinoline derivative)Nitrogen-containing compounds with potent pharmacological effects
Representative pattern: C₉H₇N₂O
Atoms
Nitrogen
Carbon
Hydrogen
Oxygen
Related Compounds (Isoquinoline alkaloid (benzylisoquinoline derivative))
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