Dehydrocorybulbine (DHCB)

Clinical trial

Isoquinoline alkaloid (benzylisoquinoline derivative)

Mechanism of Action

D2 dopamine receptor antagonist; monoamine reuptake inhibition (dopamine, serotonin); opioid receptor modulation; analgesic without respiratory depression

Research Notes

Corydalis (Yan Hu Suo)Western

DHCB is the primary alkaloid in corydalis with clinical evidence for moderate pain relief and migraine prevention in Chinese traditional medicine. Shows analgesic efficacy comparable to some weak opioids without respiratory depression or high addiction risk; mechanisms primarily dopaminergic and monoaminergic.

Found In 1 Herb

Corydalis (Yan Hu Suo)

Western

3D Molecular Structure

Isoquinoline alkaloid (benzylisoquinoline derivative)

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Dehydrocorybulbine (DHCB)

Isoquinoline alkaloid (benzylisoquinoline derivative)Nitrogen-containing compounds with potent pharmacological effects

Representative pattern: C₉H₇N₂O

Atoms

Nitrogen

Carbon

Hydrogen

Oxygen

Related Compounds (Isoquinoline alkaloid (benzylisoquinoline derivative))

Californidine(1)Tetrahydropalmatine (THP)(1)

Live Research

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